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  • Michael R. Bristow, Leslie A. Saxon, +9 authors Arthur M Feldman
  • Medicine
  • The New England journal of medicine
  • 2004 (First Publication: 20 May 2004)
  • BACKGROUND We tested the hypothesis that prophylactic cardiac-resynchronization therapy in the form of biventricular stimulation with a pacemaker with or without a defibrillator would reduce the riskContinue Reading
  • Milton Packer, Michael R. Bristow, +4 authors Neil H. Shusterman
  • Medicine
  • The New England journal of medicine
  • 1996 (First Publication: 23 May 1996)
  • BACKGROUND Controlled clinical trials have shown that beta-blockers can produce hemodynamic and symptomatic improvement in chronic heart failure, but the effect of these drugs on survival has notContinue Reading
  • Michael R. Bristow, E. Michael Gilbert, +9 authors Neil Shusterman
  • Medicine
  • Circulation
  • 1996 (First Publication: 1 December 1996)
  • BACKGROUND We conducted a multicenter, placebo-controlled trial designed to establish the efficacy and safety of carvedilol, a "third-generation" beta -blocking agent with vasodilator properties, inContinue Reading
  • Michael R. Bristow, Robert Ginsburg, +7 authors Sandra Jamieson
  • Medicine
  • Circulation research
  • 1986 (First Publication: 1 September 1986)
  • We used radioligand binding techniques and measurement of beta-agonist-mediated positive inotropic responses in isolated cardiac tissue to examine beta-adrenergic-receptor subpopulations inContinue Reading