Michael R. Atkins

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PURPOSE Several reports have shown that cells with p53 mutations display increased resistance to ionizing radiation, a treatment often used clinically for localized prostate carcinoma. MATERIALS AND METHODS Totals of 18 post-irradiated locally recurrent prostatic carcinoma specimens and 25 (no radiation) stage D1 node-positive (TxN+MO) primary prostatic(More)
Rasmussen's encephalitis is a devastating disease of childhood causing progressive neurologic deficits and intractable seizure activity. Patients frequently have episodes of epilepsia partialis continua and, much less frequently, generalized status epilepticus. The seizures are intractable despite aggressive medical management. In advanced cases,(More)
Rasmussen's syndrome (RS) is a devastating constellation of severe, unilateral focal motor epilepsy resistant to anticonvulsant therapy, followed by ipsilateral neurological deficits and neuropathological evidence of a chronic encephalitis occurring primarily in the pediatric population. Recent reports have identified viral genomic material for(More)
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