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Without an approved vaccine or treatments, Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission. These approaches, however, have yet to end the 2014 outbreak of Ebola after its prolonged presence in West Africa. Here we show that a combination of monoclonal antibodies (ZMapp), optimized from two previous(More)
Severe lower respiratory tract infection in infants and small children is commonly caused by respiratory syncytial virus (RSV). Palivizumab (Synagis(®)), a humanized IgG1 monoclonal antibody (mAb) approved for RSV immunoprophylaxis in at-risk neonates, is highly effective, but pharmacoeconomic analyses suggest its use may not be cost-effective. Previously(More)
— The industry-driven evolution of cloud computing tends to obfuscate the common underlying architectural concepts of cloud offerings and their implications on hosted applications. Patterns are one way to document such architectural principles and to make good solutions to reoccurring (architectural) cloud challenges reusable. To capture cloud computing(More)
A new kind of robots whose characteristics, objectives and operational modes drastically differ from more conventional industrial robots is gaining increased interest. This new type of robots aims to achieve a high level of flexibility, adaptability, and efficiency for acting in environments designed for humans. To meet these demands, the mobile robots need(More)
With the increasing maturity of the cloud computing market, specifically in the Infrastructure as a Service (IaaS) domain, adequate pricing of services has become a crucial success factor for providers. In this work, we take a threefold approach to examine the current situation concerning pricing in the IaaS market. Based on an initial literature review, we(More)