Michael Pauley

Learn More
In recent years, various intervention strategies have reduced malaria morbidity and mortality, but further improvements probably depend upon development of a broadly protective vaccine. To better understand immune requirement for protection, we examined liver-stage immunity after vaccination with irradiated sporozoites, an effective though logistically(More)
Motivated by the discretization problem in isogeometric analysis, we consider the challenge of segmenting a contractible boundary-represented solid into a small number of topological hexahedra. A satisfactory segmentation of a solid must eliminate non-convex edges because they prevent regular parameterizations. Our method works by searching a sufficiently(More)
We present a novel technique for segmenting a three-dimensional solid with a 3-vertex-connected edge graph consisting of only convex edges into a collection of topological hexahedra. Our method is based on the edge graph, which is defined by the sharp edges between the boundary surfaces of the solid. We repeatedly decompose the solid into smaller solids(More)
Geodesics are a generalisation of straight lines to Riemannian manifolds and other spaces equipped with an affine connection. Interpolation and approximation problems motivate analogous generalisations of cubic polynomials. There are several approaches. Cubic polynomials in Euclidean space are critical points of the mean norm-squared acceleration,(More)
Desargues: A Finite Geometry Package John Bamberg I will speak about a finite geometry package for GAP, which is a collaborative effort of Anton Betten, Jan De Beule, Maska Law, Max Neunhöffer, Michael Pauley, Sven Reichard, and myself. At the moment, the package chiefly deals with finite projective and polar spaces, but is sufficiently well structured and(More)
A class of discrete-time random processes that have seen a wide variety of applications consists of a linear state-space model whose parameters are modulated by the state of a finite-state Markov chain. A typical way to filter such processes is with collapsing methods, which approximate the underlying distribution by a mixture of Gaussians indexed by the(More)
The finite flag-transitive linear spaces which have an insoluble automorphism group were given a precise description in [BDD+90], and their classification has recently been completed (see [Lie98] and [Sax02]). However, the remaining case where the automorphism group is a subgroup of one-dimensional affine transformations has not been classified and bears a(More)
  • 1