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Voltage-activated Ca2+ channels exist as multigene families that share common structural features. Different Ca2+ channels are distinguished by their electrophysiology and pharmacology and can be classified as either low or high voltage-activated channels. Six alpha1 subunit genes cloned previously code for high voltage-activated Ca2+ channels; therefore,(More)
The molecular diversity of voltage-activated calcium channels was established by studies showing that channels could be distinguished by their voltage-dependence, deactivation and single-channel conductance. Low-voltage-activated channels are called 'T' type because their currents are both transient (owing to fast inactivation) and tiny (owing to small(More)
We are investigating techniques for developing distributed and adaptive collections of agents that coordinate to retrieve, lter and fuse information relevant to the user, task and situation, as well as anticipate a user's information needs. In our system of agents, information gathering is seamlessly integrated with decision support. The task for which(More)
Insect neurohormones (biogenic amines, neuropeptides, and protein hormones) and their G protein-coupled receptors (GPCRs) play a central role in the control of behavior, reproduction, development, feeding and many other physiological processes. The recent completion of several insect genome projects has enabled us to obtain a complete inventory of(More)
We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and(More)
To facilitate the rapid development and open system interoper-ability of autonomous agents we need to carefully specify and effectively implement various classes of agent behaviors. Our current focus is on the behaviors and underlying architecture of WWW-based autonomous software agents that collect and supply information to humans and other computational(More)
In this paper we define the notions of agent matchmaking and brokering behaviors that are used while processing requests among initially unacquainted sets of agents. These behaviors are basic components of common organizational roles and thus must be understood by computational agents. Brokering and matchmaking behaviors can be used to construct(More)
Recently, a novel neuropeptide, CCHamide, was discovered in the silkworm Bombyx mori (L. Roller et al., Insect Biochem. Mol. Biol. 38 (2008) 1147-1157). We have now found that all insects with a sequenced genome have two genes, each coding for a different CCHamide, CCHamide-1 and -2. We have also cloned and deorphanized two Drosophila G-protein-coupled(More)