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Recent studies have identified the rs75932628 (R47H) variant in TREM2 as an Alzheimer's disease risk factor with estimated odds ratio ranging from 2.9 to 5.1. The Cache County Memory Study is a large, population-based sample designed for the study of memory and aging. We genotyped R47H in 2974 samples (427 cases and 2540 control subjects) from the Cache(More)
Active legends in cartographic animation serve the dual purpose of controlling the display of a map sequence and providing necessary information about the individual frames. Legends for cartographic animations have typically been implemented in a non-interactive form as individual legends that are synchronized with the display of the map. An active legend(More)
Current demands for graduates of Information Technology (IT) programs require that they possess deep technical skills, multidisciplinary awareness, and the ability to deliver the value of technical skills to customers and clients. In order to produce this kind of IT professional, secondary and post-secondary educational institutions must embrace this(More)
Problem-based Learning (PBL) has become a popular method of instruction among educators in the health professions. Central to the effectiveness of PBL is the ability of students to work together to solve problems. When these abilities are lacking, PBL outcomes can be compromised. Since these skills have not been emphasized in public school or higher(More)
The Lecture Notes in Geoinformation and Cartography series provides a contemporary view of current research and development in Geoinformation and Cartography, including GIS and Geographic Information Science. Publications with associated electronic media examine areas of development and current technology. Editors from multiple continents, in association(More)
OBJECTIVE To review the literature on inverting papilloma of the middle ear and mastoid with a focus on familiarizing clinicians with its presentation and cause and to discuss its epidemiologic, diagnostic, and therapeutic issues. STUDY DESIGN Search of the English literature for cases of inverted papilloma of temporal bone in conjunction with 1 new case(More)
Coccidioidomycosis (‘Valley Fever’), caused by the inhalation of the fungus Coccidioides, remains a recalcitrant health problem in large parts of California. The incidence and severity of the disease continues to rise in many parts of the state. In this manuscript, we highlight unanswered questions about the disease. Specifically, the extent of disease(More)
Many organizations are not able to protect their assets from hackers or attackers until their systems or businesses are affected. The security specification process provides an organization with a proactive approach to operate in the most cost efficient manner with a known and acceptable level of security risk. In this paper, we have addressed IT security(More)
This paper analyzed the spatial patterns of four types of crime (assault, robbery, autotheft, and burglary) and their relationship with neighbourhood characteristics in the City of Omaha, Nebraska by using geographic information systems procedures and ordinary least square regression methods. Location quotients of crime and crime density were employed as(More)