Michael Nayhouse

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In this work, the modeling and control of a batch crystallization process used to produce tetragonal hen egg white lyso-zyme crystals are studied. Two processes are considered, crystal nucleation and growth. Crystal nucleation rates are obtained from previous experiments. The growth of each crystal progresses via kinetic Monte Carlo simulations comprising(More)
In this paper, we focus on a batch protein crystallization process used to produce tetragonal hen egg white lysozyme crystals and present a comparative study of the performance of a model predictive control (MPC) strategy formulated to account for crystal shape and size distribution with conventional operating strategies used in industry, namely, constant(More)
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