Michael N. Nelson

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The Sprite network operating system uses large main-memory disk block caches to achieve high performance in its file system. It provides non-write-through file caching on both client and server machines. A simple cache consistency mechanism permits files to be shared by multiple clients without danger of stale data. In order to allow the file cache to(More)
A description is given of Sprite, an experimental network operating system under development at the University of California at Berkeley. It is part of a larger research project, SPUR, for the design and construction of a high-performance multiprocessor workstation with special hardware support of Lisp applications. Sprite implements a set of kernel calls(More)
OBJECTIVE In fragile X syndrome (FXS), it is hypothesized that absence of the fragile X mental retardation protein (FMRP) disrupts regulation of group 1 metabotropic glutamate receptor (mGluR and mGluR5)-dependent translation in dendrites. Lithium reduces mGluR-activated translation and reverses phenotypes in the dfxr mutant fly and fmr1 knockout mouse.(More)
In most cases symptoms of autism begin in early infancy. However, a subset of children appears to develop normally until a clear deterioration is observed. Many parents of children with "regressive"-onset autism have noted antecedent antibiotic exposure followed by chronic diarrhea. We speculated that, in a subgroup of children, disruption of indigenous gut(More)
In this paper we describe an architecture for extensible file systems. The architecture enables the extension of file system functionality by composing (or stacking) new file systems on top of existing file systems. A file system that is stacked on top of an existing file system can access the existing file system's files via a well-defined naming interface(More)
This study investigates the Third Edition of the Bayley Scales of Infant and Toddler Development (Bayley-III) and: (1) early patterns of neurodevelopmental performance among preterm infants 8-12 months of age; and (2) correlations between known risk factors and neurodevelopmental outcome of preterm infants in this cohort. Mean Language Index (LI; 91±15) and(More)