Michael Macdonald

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Cystic fibrosis is the most common autosomal recessive disorder in Caucasian populations, with an approximate frequency of 1/2500 live births and a carrier frequency of 1/25. Due to the high rate of predicted carriers (> 63,000) in the Nebraska population (1990 U.S. Census = 1,578,358), we analyzed sperm DNA obtained from semen donors at the University of(More)
BACKGROUND Dysregulation of salivary immunoglobulins has been implicated in illnesses ranging from periodontal disease to HIV aids and malignant cancers. Despite these advances there is a lack of agreement among studies with regard to the salivary immunoglobulin levels in healthy controls. METHODOLOGY Resting and mechanically stimulated saliva samples and(More)
We report the development of eight polymorphic microsatellite loci for the Greater Roadrunner (Geococcyx californianus), a terrestrial cuckoo distributed in the US Southwest and Mexico. These markers will be useful for population genetics and molecular ecology studies of this bird.
A one in 20 sample of patients aged 18 and over registered at a health centre in Sidmouth were interviewed in their homes. Information about their personal characteristics was related to patients' use of the centre. A majority of patients found the facilities satisfactory and approved of the health-centre concept. Suggestions for improvements were also(More)
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