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Single fibril growth kinetics of α-synuclein.
Neurodegenerative disorders associated with protein misfolding are fatal diseases that are caused by fibrillation of endogenous proteins such as α-synuclein (α-syn) in Parkinson's disease (PD) orExpand
  • 35
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Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.
Conversion of the intrinsically disordered protein α-synuclein (α-syn) into amyloid aggregates is a key process in Parkinson's disease. The sequence region 35-59 contains β-strand segments β1 and β2Expand
  • 19
Uncovering the Binding and Specificity of β-Wrapins for Amyloid-β and α-Synuclein.
Amyloidogenic proteins amyloid-β peptide (Aβ) and α-synuclein (α-syn) self-assemble into fibrillar amyloid deposits, senile plaques and Lewy bodies, pathological features of Alzheimer's andExpand
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