Michael M. Abecassis

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Proteomic technology has advanced steadily since the development of 'soft-ionization' techniques for mass-spectrometry-based molecular identification more than two decades ago. Now, the large-scale analysis of proteins (proteomics) is a mainstay of biological research and clinical translation, with researchers seeking molecular diagnostics, as well as(More)
UNLABELLED : Induced pluripotent stem cells (iPSCs) are new diagnostic and potentially therapeutic tools to model disease and assess the toxicity of pharmaceutical medications. A common limitation of cell lineages derived from iPSCs is a blunted phenotype compared with fully developed, endogenous cells. We examined the influence of novel three-dimensional(More)
The national demand for kidney transplantation far outweighs the supply of kidney organs. Currently, a patient's ability to receive a kidney transplant varies depending on where he or she seeks transplantation. This reality is in direct conflict with a federal mandate from the Department of Health and Human Services. We analyze current kidney allocation and(More)
Current strategies to improve graft outcome following kidney transplantation consider information at the human leukocyte antigen (HLA) loci. Cell surface antigens, in addition to HLA, may serve as the stimuli as well as the targets for the anti-allograft immune response and influence long-term graft outcomes. We therefore performed exome sequencing of DNA(More)
OBJECTIVE Urgent clinician-clinician communications require routes of contact that are fast and dependable, and allow for the exchange of complex information. Despite the increasing focus on improving healthcare delivery systems over the past decade, few studies have examined the role of technology in clinician-clinician communication. The aim of this study(More)
One Sentence Summary: Prediction of long-term kidney graft function with exome sequencing 28 29 30. CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Exome Sequencing and Prediction of Long-Term Kidney Allograft Function, Mesnard et al. 2015 2 31(More)
This document has been developed by the American College of Surgeons (ACS) as an aid for surgeons exploring new payment approaches. The document may not be used in any way that violates law or the rights of any party. The document is to be used for informational purposes, and is not intended as and does not constitute legal, accounting, or career advice.(More)
As a clinical investigator, plastic surgeon and previous training program director, Dr. Walton is poised to contribute great things to the rich tradition of laboratory and clinical research in the Division of Plastic Surgery. The division is well known for its dedication to cutting-edge cosmetic and recon-structive surgery. Dr. Walton, a nationally renowned(More)
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