Michael Lierz

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Hepatitis E is an increasingly diagnosed human disease in Central Europe. Besides domestic pigs, in which hepatitis E virus (HEV) infection is highly prevalent, wild boars have been identified as a possible source of human infection. In order to assess the distribution of HEV in the wild boar population of Germany, we tested liver samples originating from(More)
A novel highly pathogenic Sarcocystis species has been shown to cycle between the Northern goshawk (Accipiter gentilis) as definitive host and the domestic pigeon (Columba livia f. domestica) as intermediate host. However, genetically based characteristics are only available from very few bird-infecting Sarcocystis species. We therefore further(More)
We found antibodies to leptospires in 25 (18%) of 141 wild boars from Berlin (95% confidence interval 12-25). Seropositivity was associated with chronic interstitial nephritis (odds ratio 10.5; p=0.01), and leptospires were detected in kidney tissues. Wild boars represent a potential source for human leptospirosis in urban environments.
The emerging Sarcocystis calchasi induces a severe and lethal central nervous disease in its intermediate host, the domestic pigeon (Columba livia f. domestica). Experimental studies have identified the Northern goshawk (Accipiter g. gentilis) as final host. Phylogenetically closely related European sparrowhawks (Accipiter n. nisus) and wood pigeons(More)
Sarcosporidian cysts in the skeletal muscle of domestic pigeons (Columba livia f. domestica) have previously been attributed to infection with Sarcocystis falcatula, which is shed in the faeces of the opossum (Didelphis virginiana). Here, we describe fatal spontaneous encephalitis and myositis associated with Sarcocystis infections in three flocks of racing(More)
In 2005 and 2006, Francisella tularensis unexpectedly reemerged in western Germany, when several semi-free-living marmosets (Callithrix jacchus) in a research facility died from tularemia and a group of hare hunters became infected. It is believed that hunters may have an elevated risk to be exposed to zoonotic pathogens, including F. tularensis. A previous(More)
West Nile virus (WNV) is a zoonotic flavivirus that is transmitted by blood-suckling mosquitoes with birds serving as the primary vertebrate reservoir hosts (enzootic cycle). Some bird species like ravens, raptors and jays are highly susceptible and develop deadly encephalitis while others are infected subclinically only. Birds of prey are highly(More)
Avian bornavirus (ABV) is the presumed causative agent of proventricular dilatation disease (PDD), a major fatal disease in psittacines. However, the influencing factors and pathogenesis of PDD are not known and natural ABV infection exhibits remarkable variability. We investigated the course of infection in 18 cockatiels that were intracerebrally and(More)
1. Tertti R, Vuento R, Mikkola P, Granfors K, Mäkelä A-l, Toivanen A. Clinical manifestations of Yersinia pseudotuberculosis infection in children. Eur J Clin Microbiol Infect Dis. 1989;8:587–91. DOI: 10.1007/ BF01968134 2. Nowgesic E, Fyfe M, Hockin J, King A, Ng H, Paccagnella A, et al. Outbreak of Yersinia pseudotuberculosis in British Columbia⎯November(More)