Michael Lichtwarck-Aschoff

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When managing patients with acute respiratory distress syndrome (ARDS), respiratory system compliance is usually considered first and changes in resistance, although recognized, are neglected. Resistance can change considerably between minimum and maximum lung volume, but is generally assumed to be constant in the tidal volume range (V(T)). We measured(More)
Rapid airway occlusions during mechanical ventilation are followed immediately by high-frequency pressure oscillations. To answer the question if the frequency of forced pressure oscillations is an indicator for partial obstruction of the endotracheal tube (ETT) we performed mathematical simulations and studies in a ventilated physical lung model.(More)
BACKGROUND Tracheal pressure (P(tr)) is required to measure the resistance of the tracheal tube and the breathing circuit. P(tr) can either be measured with a catheter or, alternatively, calculated from the pressure-flow data available from the ventilator. METHODS Calculated P(tr) was compared with measured P(tr) during controlled ventilation and assisted(More)
In various cardio-pulmonary diseases lung mass is considerably increased due to intrapulmonary fluid accumulation, i.e. extravascular lung water (EVLW). Generally, inertance is a physical system parameter that is mass-dependent. We hypothesized that changes in lung mass influence the inertive behavior of the respiratory system. EVLW and intrathoracic blood(More)