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Support for fine-grained data management has all but disappeared from modern operating systems such as An-droid and iOS. Instead, we must rely on each individual application to manage our data properly – e.g., to delete our emails, documents, and photos in full upon request; to not collect more data than required for its function; and to back up our data to(More)
BACKGROUND Etoricoxib is a highly selective COX-2 inhibitor which was evaluated for the treatment of rheumatoid arthritis (RA). METHODS Double-blind, randomized, placebo and active comparator-controlled, 12-week study conducted at 67 sites in 28 countries. Eligible patients were chronic NSAID users who demonstrated a clinical worsening of arthritis upon(More)
It has become increasingly apparent that one of the major hurdles in the genomic age will be the bioinformatics challenges of next-generation sequencing. We provide an overview of a general framework of bioinformatics analysis. For each of the three stages of (1) alignment, (2) variant calling, and (3) filtering and annotation, we describe the analysis(More)
In this report we present our tools for prototyping adaptive user interfaces in the context of real—time musical instrument control. Characteristic of most human communication is the simultaneous use of classified events and estimated parameters. We have integrated a neural network object into the MAX language to explore adaptive user interfaces that(More)
The advent of serial communication links in chip-to-chip and systemto-system applications has resulted in intense focus on jitter and BER testing techniques, including jitter generation and measurement methodologies. We describe techniques for injection of random and deterministic jitter in controlled and programmable fashion, including a novel(More)
A 31-year-old Chinese man with intractable severe, lifelong Tourette's syndrome characterised by forceful self-injurious motor tics and socially embarrassing vocal tics was treated with bilateral deep brain stimulation. Electrodes were implanted into the thalamic targets at the centromedian-parafascicular complex according to Hassler's nomenclature. A(More)
Judgment and decision making research overwhelmingly uses null hypothesis significance testing as the basis for statistical inference. This article examines an alternative, Bayesian approach which emphasizes the choice between two competing hypotheses and quantifies the balance of evidence provided by the data—one consequence of which is that experimental(More)
BACKGROUND Cognitive domain deficits can occur after aneurysmal subarachnoid haemorrhage (aSAH) though few studies systemically evaluate its impact on 1-year outcomes. OBJECTIVE We aimed to evaluate the pattern and functional outcome impact of cognitive domain deficits in aSAH patients at 1 year. METHODS We carried out a prospective observational study(More)