Michael Lang

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Tissue engineering is a rapidly growing field with the aim of developing replacement tissues and organs for patients. An important aspect to the success of regenerated tissue is in the seeding of cells into structured porous scaffolds. This paper reports on an integrated system that is capable of printing bio-scaffold structures and automating the process(More)
Most living species exploit a limited range of resources. However, little is known about how tight associations build up during evolution between such specialist species and the hosts they use. We examined the dependence of Drosophila pachea on its single host, the senita cactus. Several amino acid changes in the Neverland oxygenase rendered D. pachea(More)
There is a growing interest in the evolution of transcription factor binding sites and corresponding functional change of transcriptional regulation. In this context, we have examined the structural changes of the ADF-1 binding sites at the Adh promoters of Drosophila funebris and D. virilis. We detected an expanded footprinted region in D. funebris that(More)
Tissue engineering is an emerging discipline which seeks to overcome many of the limitations of current surgical approaches for the treatment of tissue and organ loss. The approach utilises patient derived biological tissue replacements. Traditional tissue engineering approaches involve the seeding of suspended single cells onto the surface of a 3D porous(More)
Multiple animal species exhibit morphological asymmetries in male genitalia. In insects, left-right genital asymmetries evolved many times independently and have been proposed to appear in response to changes in mating position. However, little is known about the relationship between mating position and the interaction of male and female genitalia during(More)
Magnetic resonance imaging (MRI) studies are currently being performed at the Health Sciences Center (HSC) in Winnipeg in order to understand better central nervous system (CNS) disorders. Using a 7-Tesla MRI system and rodent models of Alzheimer's disease and Multiple Sclerosis, novel MRI techniques are being exploited to enhance the diagnosis of these(More)
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