Michael L. Harrison

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Syk (p72syk) is a 72-kDa, nonreceptor, protein-tyrosine kinase that becomes tyrosine-phosphorylated and activated in B lymphocytes following aggregation of the B-cell antigen receptor. To explore the subcellular location of activated Syk, anti-IgM-activated B-cells were fractionated into soluble and particulate fractions by ultracentrifugation. Activated(More)
For many applications it is not enough for a system to perform correctly under ideal circumstances. Systems benefit from robust and survivable designs that can withstand faults and degrade gracefully as faults occur. System topologies that resist component failures are certainly attractive in many applications. We demonstrate the effectiveness of a(More)
Field studies on callitrichid primates have suggested that some species may exhibit a communal breeding system in which two or more males mate with a single female and cooperatively participate in infant rearing. However, high levels of aggression have been observed between males under both laboratory and field conditions. In avian models for communal(More)
A 19-year-old child became disoriented and ataxic 6 days after a diphtheria-pertussis-tetanus (DPT) booster injection. Computerized tomographic scan revealed a hyperdense mesencephalic-pontine mass, and angiography demonstrated an avascular mass. Pontine biopsy revealed no abnormality. Her clinical course fluctuated until her death 15 months later. At(More)
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