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BACKGROUND Polyhydroxyalkanoates (PHAs) can be degraded by many microorganisms using intra- or extracellular PHA depolymerases. PHA depolymerases are very diverse in sequence and substrate specificity, but share a common alpha/beta-hydrolase fold and a catalytic triad, which is also found in other alpha/beta-hydrolases. RESULTS The PHA Depolymerase(More)
To obtain the highest-resolution ray-based tomographic images from crosshole ground-penetrating radar ͑GPR͒ data, wide angular ray coverage of the region between the two boreholes is required. Unfortunately, at borehole spacings on the order of a few meters, high-angle traveltime data ͑i.e., traveltime data corresponding to transmitter-receiver angles(More)
In this study, we investigate the use of crosswell P-wave seismic tomography to obtain spatially extensive information about subsurface sedimentary architecture and hetero-geneity in alluvial aquifers. Our field site was a research wellfield in an unconfined aquifer near Boise, Idaho. The aquifer consists of a ϳ 20-m-thick sequence of alluvial cobble and(More)
—This paper presents a high-performance maximum power point tracker (MPPT) optimized for fast cloudy conditions, e.g., rapidly changing irradiation on the photovoltaic panels. The rapidly changing conditions are tracked by an optimized hill– climbing MPPT method called dP-P&O. This algorithm separates the effects of the irradiation change from the effect of(More)
The Medium-Chain Dehydrogenase/Reductase Engineering Database (MDRED, http://www.mdred.uni-stuttgart.de) has been established to serve as an analysis tool for a systematic investigation of sequence-structure-function relationships. It includes sequence and structure information of 2684 and 42 medium-chain dehydrogenases/reductases (MDRs), respectively.(More)
Immunoliposomes generated by coupling of antibodies to the liposomal surface allow for an active targeting of entrapped compounds to diseased areas. Single-chain Fv fragments (scFv) represent the smallest part of an antibody containing the entire antigen-binding site. They can be coupled in a defined and site-directed manner through genetically engineered(More)
Major horizons in radar reflection profiles may correlate with contacts between stratigraphic units or with structural breaks such as fault surfaces. Minor reflections may be caused by clutter or, in some cases, may indicate material properties or structure within stratigraphic units. In this study, we examine the physical basis for major and minor(More)
SUMMARY The Cytochrome P450 Engineering Database (CYPED) has been designed to serve as a tool for a comprehensive and systematic comparison of protein sequences and structures within the vast and diverse family of cytochrome P450 monooxygenases (CYPs). The CYPED currently integrates sequence and structure data of 3911 and 25 proteins, respectively. Proteins(More)