Michael Kleinberger

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Patients with chronic active Crohn's disease are dependent on systemic glucocorticosteroids. The aim of the study was to investigate the efficacy of budesonide, a topically selective glucocorticosteroid, as therapy in these patients. We investigated 20 patients with chronic active Crohn's disease. During the last 6 months prior to the study the patients had(More)
he lack of predictive tools to assess the relative risk of stress fracture injury has posed a great challenge for military readiness and competitive athletic training. This article presents a methodology of assessing such risks using computational models and biomechanical stress analysis in a human femur. Preliminary results have demonstrated the capability(More)
Although whiplash is typically classified as a minor injury, the economic cost ofwhiplash has been estimated at roughly $4.5 billion per year in the United States. International research efforts have included computational modeling, crash reconstructions, biomechanical testing of animals and human cadavers, and experimental rear impact tests using both(More)
OBJECTIVE To determine the effect of aging on the occurrence of femoral and tibial fractures during vehicular crashes. METHODS The Crash Injury Research and Engineering Network (CIREN), which includes occupants of a vehicle < 8 years old with at least one AIS > or = 3 or two AIS > or = 2 injuries in different body regions, comprised the study population.(More)
The objective of the study was to develop a simple device, Vertical accelerator (Vertac), to apply vertical impact loads to Post Mortem Human Subject (PMHS) or dummy surrogates because injuries sustained in military conflicts are associated with this vector; example, under-body blasts from explosive devices/events. The two-part mechanically controlled(More)
The occurrence of AI was studied in relation to vehicle model year (MY) among front seat vehicular occupants, age≥16 in vehicles MY≥1994, entered in the National Automotive Sampling System Crashworthiness Data System between 1997 and 2010 to determine whether newer vehicles, due to their crashworthiness improvements, are linked to a lower risk of aortic(More)
This purpose of this study was to replicate foot–ankle injuries seen in the military and derive human injury probability curves using the human cadaver model. Lower legs were isolated below knee from seventeen unembalmed human cadavers and they were aligned in a 90–90 posture (plantar surface orthogonal to leg). The specimens were loaded along the tibia(More)
Traffic safety has significantly improved over the past several decades reducing injury and fatality rates. However, there is a paucity of research effort directed to address the safety issues in off-highway vehicular crashes, specifically the all terrain/utility vehicular crashes. Rollover crashes are severe accidents leading to the increase in fatalities(More)
hroughout the evolution of military helmet systems, the amount of head-supported mass (HSM) worn by Army personnel has steadily increased. The U.S. Army Aeromedical Research Laboratory is working to establish recommended limits and guidelines for HSM that can be worn safely by soldiers. To support this effort, crash sled tests were conducted at APL’s Impact(More)