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Family involvement is an essential element of language intervention with severely handicapped children for several reasons. First, the parent-child interaction is the focus of normal language development, and can be a powerful impetus in language learning for handicapped children. Second, limited generalization and maintenance of skills often occur when(More)
Renal units associated with reflux in the spinal cord-injured (SCI) patient have a greater incidence of kidney stones developing than in the nonrefluxing units. It is logical to assume that SCI patients with persistent reflux and bladder stones treated with cystolitholapaxy would be at even higher risk for kidney stones developing. Of the 898 SCI patients(More)
To determine the incidence and effects of low bladder compliance on the upper urinary tracts in spinal cord injury patients, we evaluated the last 254 patients during a 3-year period who underwent a complete urodynamic study, along with an excretory urogram and/or renal ultrasound. Compliance was determined at 100 cc volume. A compliance number of 20 or(More)
Chronic infection of the human stomach by Helicobacter pylori leads to a variety of pathological sequelae, including peptic ulcer and gastric cancer, resulting in significant human morbidity and mortality. Several genes have been implicated in disease related to H. pylori infection, including the vacuolating cytotoxin and the cag pathogenicity island. Other(More)
OBJECTIVE To determine the feasibility and test characteristics of optic nerve sheath diameter (ONSD) measured by ocular ultrasound as a screening tool for ventriculoperitoneal shunt (VPS) failure. METHODS Prospective observational study using a convenience sample of children 6 months to 18 years of age, presenting to an academic pediatric emergency(More)
Nitric oxide (NO) has come far since being discovered serendipitously to relax vascular smooth muscle. Initially, administered to animals to reduce pulmonary artery pressures and improve oxygenation. It now enjoys FDA approval for administration to newborns with pulmonary hypertension but is used common place for other critical cardiopulmonary ailments.(More)
Prediction of human clearance plays a critical role in early drug discovery and development. However, there is no consensus on the most appropriate method to gather such data. A variety of in vivo and in vitro methods exist and a comparison of in vitro data from a standard set of compounds has been called for. This paper compares the predictive capacity of(More)
BACKGROUND As patients directly experience harm from adverse events, investigators have proposed patient-report to complement professional reporting of adverse events. OBJECTIVE To investigate how an automated health assessment system can be used to identify adverse events. DESIGN AND SETTING Internet survey responses from April 2003 to April 2005(More)
A general purpose wideband radio channel model implemented in MATLAB has been designed specifically for testing the performance of wideband chaotic communication systems utilising a radio interface. The theoretical basis of the model is presented in the paper, as well as a short description of the MATLAB program and some illustrative examples of the output(More)
—In this paper, a predictive closed power control loop for mobile communication systems is simulated employing actual multiuser interference. The system parameters are derived from those used in a CDMA system uplink transmission at urban mobile speeds. It is shown by COSSAP (Communications Simulation and System Analysis Program of CADIS GmbH, Germany)(More)