Michael James Zema

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Thirty-seven patients were evaluated before cardiac catheterisation by bedside physical examination, including Valsalva manoeuvre, to assess the value of the sphygmomanometrically determined arterial pressure responses during the Valsalva manoeuvre and to compare its sensitivity, specificity, and predictive accuracy in the detection of left ventricular(More)
Thirty-seven patients with dyspnea, clinical chronic obstructive pulmonary disease and abnormal pulmonary function tests demonstrating an obstructive airways pattern underwent six-foot posteroanterior chest radiography, radionuclide ventriculography and sphygmomanometer-monitored arterial pressure response during a bedside Valsalva maneuver. Patients could(More)
Colesevelam hydrochloride is a molecularly engineered, second-generation bile acid sequestrant demonstrating enhanced specificity for bile acids which has been approved for use as adjunctive therapy to diet and exercise as monotherapy or in combination with a β-hydroxymethylglutaryl-coenzyme A reductase inhibitor for the reduction of elevated low-density(More)
BACKGROUND Both colesevelam hydrochloride (colesevelam) and ezetimibe monotherapy have been reported to lower low-density lipoprotein cholesterol (LDL-C) approximately 15-17% in patients with hypercholesterolemia. When statin therapy is inadequate to reach desired LDL-C goals, the choice of add-on therapy, while multifactorial, must consider efficacy of(More)
Creatine kinase-MB isoenzyme release (CK-MB-g-Eq) was correlated with left ventricular (LV) radionuclide gated blood pool wall motion estimates of percent abnormally contracting regions (%ACR), ejection fraction (EF) and quantitative thallium-201 (Tl-201) LV perfusion scintigraphy (Tl-201 perfusion index) during evolving myocardial infarction (MI). Of the(More)
The use of digitalis after acute myocardial infarction is controversial. The effect of digoxin on computer-quantitated thallium-201 perfusion scintigrams (Tl-201), left ventricular (LV) ejection fraction (EF), and percentage of abnormally contracting LV regions (% ACR) was determined in 23 patients. A correlation was established between creatine kinase MB(More)
Fifty-six patients with "poor R wave progression" (PRWP) on the electrocardiogram (ECG) were studied by Frank vectorcardiography in an attempt to define discriminators for subgroups. Criteria were prospectively applied to a test group with achievement of comparable sensitivity and specificity. Four subgroups were identified in the patients with PRWP: Group(More)
The bedside sphygmomanometric determination of the arterial pressure response during the Valsalva maneuver was incorporated into the routine physical examination of ambulatory subjects. Four distinct Valsalva responses were noted: ultrasinusoidal, sinusoidal, absent overshoot, and square wave. The absent overshoot response was further divided into(More)