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  • Hao Li, Jonathan C Radford, +11 authors Stuart A Lipton
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2008 (First Publication: 8 July 2008)
  • Emerging evidence suggests that myocyte enhancer factor 2 (MEF2) transcription factors act as effectors of neurogenesis in the brain, with MEF2C the predominant isoform in developing cerebrocortex.Continue Reading
  • Michael J Ragusa, Barbara Dancheck, David A. Critton, Angus C. Nairn, Rebecca Page, Wolfgang Peti
  • Biology, Medicine
  • Nature Structural &Molecular Biology
  • 2010 (First Publication: 21 March 2010)
  • The serine/threonine protein phosphatase 1 (PP1) dephosphorylates hundreds of key biological targets. PP1 associates with ≥200 regulatory proteins to form highly specific holoenzymes. TheseContinue Reading
  • Joseph A. Marsh, Barbara Dancheck, Michael J Ragusa, Marc Allaire, Julie Deborah Forman-Kay, Wolfgang Peti
  • Biology, Medicine
  • Structure
  • 2010 (First Publication: 1 September 2010)
  • Complete folding is not a prerequisite for protein function, as disordered and partially folded states of proteins frequently perform essential biological functions. In order to understand theirContinue Reading
  • Barbara Dancheck, Michael J Ragusa, Marc Allaire, Angus C. Nairn, Rebecca Page, Wolfgang Peti
  • Chemistry, Medicine
  • Biochemistry
  • 2011 (First Publication: 22 February 2011)
  • Regulation of the major Ser/Thr phosphatase protein phosphatase 1 (PP1) is controlled by a diverse array of targeting and inhibitor proteins. Though many PP1 regulatory proteins share at least oneContinue Reading