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Many agent-based modeling and simulation researchers and practitioners have called for varying levels of simulation interoperability ranging from shared software architectures to common agent communications languages. These calls have been at least partially answered by several specifications and technologies. In fact, Tanenbaum [1988] has remarked that the(More)
Purpose: This paper is to describe development of the features and functions of Repast Simphony, the widely used, free, and open source agent-based modeling environment that builds on the Repast 3 library. Repast Simphony was designed from the ground up with a focus on well-factored abstractions. The resulting code has a modular architecture that allows(More)
MOTIVATION In recent years, single-cell biology has focused on the relationship between the stochastic nature of molecular interactions and variability of cellular behavior. To describe this relationship, it is necessary to develop new computational approaches at the single-cell level. RESULTS We have developed AgentCell, a model using agent-based(More)
Agent-based modeling and simulation (ABMS) is a new approach to modeling systems comprised of interacting autonomous agents. ABMS promises to have far-reaching effects on the way that businesses use computers to support decision-making and researchers use electronic laboratories to do research. Some have gone so far as to contend that ABMS is a new way of(More)
Agent-based modeling and simulation (ABMS) is a new approach to modeling systems comprised of autonomous, interacting agents. ABMS promises to have far-reaching effects on the way that businesses use computers to support decision-making and researchers use electronic laboratories to support their research. Some have gone so far as to contend that ABMS is a(More)
The use of object-orientation for both spatial data and spatial process models facilitates their integration, which can allow exploration and explanation of spatial-temporal phenomena. In order to better understand how tight coupling might proceed and to evaluate the possible functional and efficiency gains from such a tight coupling, we identify four key(More)
Agent-based modeling and simulation (ABMS) is a new approach to modeling systems comprised of autonomous, interacting agents. ABMS promises to have far-reaching effects on the way that businesses use computers to support decision-making and researchers use electronic laboratories to support their research. Some have gone so far as to contend that ABMS "is a(More)
Agent-based modeling and simulation (ABMS) is an approach to modeling systems comprised of individual, autonomous, interacting "agents." There is much interest in many application problem domains in developing agent-based models. Agent-based modeling offers ways to model individual behaviors and how behaviors affect others in ways that have not been(More)