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As part of the genotoxic stress response, cells activate the transcription factor NF-κB. The DNA strand break sensor poly(ADP-ribose)-polymerase-1 (PARP-1) and the kinase ataxia telangiectasia… Continue Reading
The RNA-binding protein RC3H1 (also known as ROQUIN) promotes TNFα mRNA decay via a 3'UTR constitutive decay element (CDE). Here we applied PAR-CLIP to human RC3H1 to identify ∼ 3,800 mRNA targets… Continue Reading
The RNA-binding protein RC3H1 (also known as ROQUIN) promotes TNFa mRNA decay via a 30UTR constitutive decay element (CDE). Here we applied PAR-CLIP to human RC3H1 to identify B3,800 mRNA targets… Continue Reading
This paper introduces the electrically detected displacement assay (EDDA), a electrical biosensor detection principle for applications in medical and clinical diagnosis, and compares the method to… Continue Reading
The new tungstovanadate (III) crystallizes in the monoclinic space group P21/m with Z = 2 (single crystal XRD).
Although human endogenous retroviruses (HERVs) represent a substantial proportion of the human genome and some HERVs have been suggested to be involved in neurological disorders, little is known… Continue Reading