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Processes that enable an effective response to unexpected events and vulnerabilities that lie outside the scope of formal procedures can be described as being resilient. There are many such descriptions of resilience within and across different domains. Comparison and generalisation is difficult because resilience is not a component of a system and should(More)
Recently, a DNA binding protein 'PUF' was purified that binds to a poly-pyrimidine rich element in the human c-myc promoter. Cloning of the corresponding gene surprisingly identified this putative transcription factor as isoform B of the enzyme nucleoside diphosphate kinase (NDPK-B) [Postel et al. (1993) Science, 261, 478-480], the product of the potential(More)
Nucleoside diphosphate (NDP) kinase has a central role in the synthesis of (deoxy-)trinucleotides. In addition, mutations in the gene encoding NDP kinase have been shown to have important consequences for Drosophila development and mammalian tumorogenesis. We have overexpressed, in Dictyostelium discoideum, a genomic clone encoding the enzyme NDP kinase.(More)
A comparison of tissue cutting effects in excised cadaver human vocal folds after incisions with three different instruments [scalpel, CO2 laser and the picosecond infrared laser-(PIRL)] was performed. In total, 15 larynges were taken from human cadavers shortly after death. After deep freezing and thawing for the experiment, the vocal folds suspended in(More)
Resilience markers for safer systems and organisations. Abstract. If computer systems are to be designed to foster resilient performance it is important to be able to identify contributors to resilience. The emerging practice of Resilience Engineering has identified that people are still a primary source of resilience, and that the design of distributed(More)
The goal of this workshop is to explore and support the design of temporal aspects of interactive systems. Time design is an emerging research and development domain that emphasizes the functional, causal role of time in human-device interaction. It draws on a diverse literature on time in cognitive psychology, psychophysics, sociology, computer science,(More)
This paper explores temporal aspects of control behavior in order to support the design of systems where functions can be allocated flexibly in time. Dynamic Function Scheduling, an extension of Dynamic Function Allocation approaches, highlights the role of temporal information and temporal reasoning in supervisory control decisions. The microworld(More)