Learn More
BACKGROUND Patients with acute kidney injury (AKI) requiring initiation of renal replacement therapy (RRT) have poor short- and long-term outcomes, including the development of dialysis dependence. Currently, little is known about what factors may predict renal recovery in this population. METHODS We conducted a single-center, retrospective analysis of(More)
STUDY OBJECTIVE To investigate oseltamivir and oseltamivir carboxylate pharmacokinetics in critically ill patients who were receiving continuous venovenous hemodialysis (CVVHD) and/or extracorporeal membrane oxygenation (ECMO). DESIGN Prospective, open-label, pharmacokinetic study. SETTING Intensive care units of an academic medical center. PATIENTS(More)
This paper presents a novel sensor in the form of a ring to monitor vascular tone continuously and non-invasively. The signal that is generated by this sensor would allow for accurate detection and analysis of reflection waves that can be used to identify or predict several medical conditions including intradialytic hypotension (IDH). The sensor is(More)
BACKGROUND Identification of acute kidney injury (AKI) can be challenging in patients with underlying chronic disease, and biomarkers often perform poorly in this population. In this study we examined the performance characteristics of the novel biomarker panel of urinary tissue inhibitor of metalloproteinases-2 (TIMP2) and insulin-like growth(More)
BACKGROUND Continuous quality improvement (CQI) has been successfully applied in business and engineering for over 60 years. While using CQI techniques within nephrology has received increased attention, little is known about where, and with what measure of success, CQI can be attributed to improving outcomes within nephrology care. This is particularly(More)
BACKGROUND Daptomycin has concentration-dependent antibacterial activity against Gram-positive bacteria. Its use is increasing in haemodialysis units. The manufacturer recommends a 4-6-mg/kg dose administered every 48 hrs for patients receiving haemodialysis. However, there are no published data about daptomycin pharmacokinetics and clearance during(More)
  • 1