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  • Dian Wang, Qiang Zhang, +8 authors Burton L. Eisenberg
  • Medicine
  • Annals of Surgical Oncology
  • 2011 (First Published: 1 July 2012)
  • BackgroundImatinib inhibits the KIT and PDGFR tyrosine kinases, resulting in its notable antitumor activity in gastrointestinal stromal tumor (GIST). We previously reported the early results of aContinue Reading
  • Timothy P Hughes, Yeow-Tee Yt Goh, +18 authors Dong-wook Kim
  • Medicine
  • 2016 (First Published: 2 December 2016)
  • Background: ABL001 is a potent, specific BCR-ABL inhibitor in development for the treatment of patients with CML and Ph+ ALL. ABL001 binds a pocket on the BCR-ABL kinase domain normally occupied byContinue Reading