Learn More
OBJECTIVE We examined the associations of clinical profiles in type 2 diabetic patients who developed severe hypoglycemia and their clinical outcomes, including death and all-site cancer. RESEARCH DESIGN AND METHODS A consecutive cohort of 8,767 type 2 diabetic patients with and without severe hypoglycemia in the 12 months before enrollment were recruited(More)
BACKGROUND Childhood and adolescence are critical periods of habit formation with substantial tracking of lifestyle and cardiovascular risk into adulthood. There are various guidelines on recommended levels of physical activity in youth of school-age. Despite the epidemic of obesity and diabetes in China, there is a paucity of data in this regard in Chinese(More)
BACKGROUND Obesity is now a global epidemic. In this study, we aimed to assess the rates of obesity using several major diagnostic criteria in Chinese school adolescents in Hong Kong. METHODS This is a cross-sectional study. Using a computer-generated coding system, we randomly selected schools from different geographical regions in Hong Kong to obtain a(More)
INTRODUCTION The association between sleep duration, obesity, and serum lipid profile in the youth population is under-explored. OBJECTIVE To evaluate the association between sleep duration, obesity and serum lipid profile in the youth population. METHODS We conducted a cross-sectional population-based study with students recruited from primary and(More)
OBJECTIVES a. Explore the stability in sleep/wake patterns of middle-aged adults over a 3-year follow-up period. b. Explore the relationship between objectively measured sleep indices, urinary catecholamines, and salivary cortisol. DESIGN Naturalistic follow-up for sleep/wake patterns (n = 114) by 2-week sleep log and cross-sectional design for objective(More)
BACKGROUND Despite parallel increases in asthma and obesity prevalence, there is little data on obesity as a risk factor for atopy. The latter is an important phenotype in asthmatic patients. This study investigates the association between asthma traits, atopy and obesity-related markers in Chinese adolescents. METHODS 486 schoolchildren were recruited(More)
OBJECTIVE To establish the reference values for serum levels of IGF-1 and IGFBP-3 and their ratio in Chinese adolescents aged 12-19 years. DESIGN AND METHODS 2102 Chinese adolescents were randomly selected from all secondary schools in Hong Kong with 1734 having IGF-1 and IGFBP-3 levels as measured by automated chemiluminescent assays (IMMULITE 2000). LMS(More)
BACKGROUND AND OBJECTIVE Agents such as Mycoplasma pneumoniae, Chlamydophila pneumoniae and Legionella pneumophila are recognized as important causes of community-acquired pneumonia (CAP) worldwide. This study examined the role of these 'atypical pathogens' (AP) among adult hospitalized patients with CAP. METHODS A prospective, observational study of(More)
OBJECTIVE To investigate the prevalence of vertebral fractures and to identify risk factors associated with vertebral fractures in Chinese women with systemic lupus erythematosus (SLE). METHODS One hundred fifty-two consecutive patients with SLE were recruited in this cross-sectional study. Bone mineral density (BMD) measurements of the hip and spine were(More)
BACKGROUND/AIMS To establish the prevalence of elevated serum alanine aminotransferase (ALT) concentrations in Chinese adolescents, and to explore the nature of associations amongst ALT, obesity and cardiovascular risk factors. METHODS Anthropometric measurements and fasting plasma glucose, insulin, lipids and ALT were measured in 2102 Chinese(More)