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This study was designed to evaluate the addition of a single-injection sciatic nerve block to a femoral nerve block for analgesia after total knee arthroplasty. Fifty-seven patients undergoing primary total knee arthroplasty were randomized to receive femoral nerve blockade or a sham block. A subsequent 31 patients received both femoral and sciatic nerve(More)
BACKGROUND AND OBJECTIVES The fentanyl HCl iontophoretic transdermal system (ITS) has been demonstrated in clinical trials to be safe and effective for acute-pain management after several types of major surgery. The current study compared the efficacy, safety, and convenience of fentanyl ITS with morphine intravenous patient-controlled analgesia (IV PCA)(More)
UNLABELLED In this randomized, double-blind, placebo-controlled, multicenter study we assessed the analgesic effect of etoricoxib (a new cyclooxygenase-2 inhibitor) in patients having had knee or hip replacement surgery. A total of 228 patients with moderate or severe pain were randomly allocated within 72 h after surgery to receive etoricoxib 120 mg,(More)
We are reporting the relatively poor results obtained in patients receiving a unicompartmental knee arthroplasty (UKA). Thirty-six patients underwent 39 UKAs from December 2002 to June 2004. All received a DePuy Preservation design (DePuy, Warsaw, In) with an all-poly tibial component. The patients' mean age was 60 years, with an equal distribution of men(More)
The ability of six commercially available orthotic knee braces to stabilize ligamentous injuries of the knee was evaluated using fresh cadaver specimens. Anterior, valgus, and rotational forces were applied to the intact knee, after the anterior cruciate and medial collateral ligaments were cut, and after application of the knee braces. Bony displacement(More)
We evaluated the results of excision of the fragment in 16 patients with symptomatic bipartite patellae. In nine, the pain began following trauma; in seven, the onset was insidious. The pain was aggravated by activity in all patients. The average age at surgery was 14 years, 6 months, and the average postoperative follow-up was 7 years. Fifteen of the(More)
Reported here is the characterization of the hairless mouse ear as a model system for defining the microvascular effects of minimal frostbite injury by means of gross, in vivo microscopic, histologic, and electron microscopic analysis. Initial efforts, using controlled temperatures and time of freezing, defined the minimum conditions necessary to produce(More)
A series of 189 consecutive posterior cruciate condylar total knee arthroplasties (TKAs) in 151 patients was reviewed. Of these, 18 patients died (22 knees), and two patients (three knees) were lost to follow-up study, leaving 164 knees in 131 patients for evaluation at 5.3 +/- 0.8 years (mean +/- SD). Before surgery 91% of the patients experienced moderate(More)
To determine the efficacy of rofecoxib in post-orthopedic surgery pain, we conducted a double-blind, randomized, placebo- and active-comparator-controlled, parallel-group trial. Two hundred eighteen patients enrolled. Day 1 patients received placebo, rofecoxib 50 mg, or naproxen sodium 550 mg. Days 2 through 5, the placebo and naproxen sodium groups(More)
Recently an increase has been shown in perioperative morbidity and mortality in patients older than 70 years undergoing sequential or simultaneous total knee arthroplasty (TKA) using 1 anesthetic. This study prospectively compared perioperative morbidity, mortality, and functional outcomes in patients 70 years and older undergoing sequential bilateral TKA(More)