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Although a previous genetic mixed-stock analysis (gMSA) conducted in the early 1990s showed that marine-captured New York Bight Atlantic sturgeon Acipenser oxyrinchus oxyrinchus almost exclusively originated from the Hudson River, fish from southern U.S. rivers were well represented within this contemporary sample (n = 364 fish), at least during the autumn.(More)
Published life-history parameters for sharks, skates, and rays over a wide geographic range were used to develop predictive models to estimate parameters that are difficult to measure or have not been previously estimated in elasmobranch species. We determined empirical relationships between body size (total length) and length at maturity (L m) and age at(More)
The historic influence of dams on diadromous fish habitat with a focus on river herring and hydrologic longitudinal connectivity version on a funder's repository at a funder's request, provided it is not made publicly available until 12 months after publication. Abstract The erection of dams alters habitat and longitudinal stream connectivity for migratory(More)
Improved treatments for heart failure patients will require the development of novel therapeutic strategies that target basal disease mechanisms. Disrupted cardiomyocyte Ca(2+) homeostasis is recognized as a major contributor to the heart failure phenotype, as it plays a key role in systolic and diastolic dysfunction, arrhythmogenesis, and hypertrophy and(More)
Although t-tubules have traditionally been thought to be absent in atrial cardiomyocytes, recent studies have suggested that t-tubules exist in the atria of large mammals. However, it is unclear whether regional differences in t-tubule organization exist that define cardiomyocyte function across the atria. We sought to investigate regional t-tubule density(More)
AIMS Invaginations of the cellular membrane called t-tubules are essential for maintaining efficient excitation-contraction coupling in ventricular cardiomyocytes. Disruption of t-tubule structure during heart failure has been linked to dyssynchronous, slowed Ca(2+) release and reduced power of the heartbeat. The underlying mechanism is, however, unknown.(More)
KEY POINTS In the majority of species, including humans, increased heart rate increases cardiac contractility. This change is known as the force-frequency response (FFR). The majority of mammals have a positive force-frequency relationship (FFR). In rat the FFR is controversial. We derive a species- and temperature-specific data-driven model of the rat(More)
Michael Frisk, Jussi T. Koivumäki, Per A. Norseng, Mary M. Maleckar, Ole M. Sejersted, and William E. Louch Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway; Center for Biomedical Computing,(More)
a r t i c l e i n f o Pikeperch is of increasing interest to the aquaculture industry, as a novel high value species. To our knowledge there is currently no information available on the metabolic rates of adult pikeperch. The present study determined the standard and maximum metabolic rates and ventilation frequency at six temperatures, ranging from 13 to(More)
Marine fish and shellfish are primary sources of human exposure to mercury, a potentially toxic metal, and selenium, an essential element that may protect against mercury bioaccumulation and toxicity. Yet we lack a thorough understanding of Hg and Se patterns in common marine taxa, particularly those that are commercially important, and how food web and(More)