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MOTIVATION Gene expression data have become an instrumental resource in describing the molecular state associated with various cellular phenotypes and responses to environmental perturbations. The utility of expression profiling has been demonstrated in partitioning clinical states, predicting the class of unknown samples and in assigning putative(More)
Barrett's esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia, and it strongly predisposes to esophageal adenocarcinoma (EAC), a tumor with a very poor prognosis. We report the first genome-wide association study on Barrett's esophagus, comprising 1,852 UK cases and 5,172 UK(More)
In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a b s t r a c t Concepts in fields such as astronomy often invoke scales of space and(More)
Previous research has suggested that faces and words are processed and remembered differently as reflected by different ERP patterns for the two types of stimuli. Specifically, face stimuli produced greater late positive deflections for old items in anterior compared to posterior regions, while word stimuli produced greater late positive deflections in(More)
There are two families of Donaldson invariants for the complex projec-tive plane, corresponding to the SU(2)-gauge theory and the SO(3)-gauge theory with non-trivial Stiefel-Whitney class. In 1997 Moore and Witten [16] conjectured that the regularized u-plane integral on CP 2 gives the generating functions for these invariants. In earlier work [15], the(More)
This Event-Related Potential (ERP) study investigated whether components commonly measured at test, such as the FN400 and the parietal old/new components, could be observed during encoding and, if so, whether they would predict different levels of accuracy on a subsequent memory test. ERPs were recorded while subjects classified pictures of objects as(More)
In his famous deathbed letter, Ramanujan introduced the notion of a mock theta function, and he offered some alleged examples. Recent work by Zwegers [Zwegers S (2001) Contemp Math 291:268-277 and Zwegers S (2002) PhD thesis (Univ of Utrecht, Utrecht, The Netherlands)] has elucidated the theory encompassing these examples. They are holomorphic parts of(More)
OBJECTIVE Familial hypercholesterolaemia (FH) affects 1 in 500 people in the UK population and is associated with premature morbidity and mortality from coronary heart disease. In 2008, National Institute for Health and Care Excellence (NICE) recommended genetic testing of potential FH index cases and cascade testing of their relatives. Commissioners have(More)
— The compensation for atmospheric effects in the VNIR/SWIR has reached a mature stage of development with many algorithms available for application (ATREM, FLAASH, ACORN, etc.). Compensation of LWIR data is the focus of a number of promising algorithms. A gap in development exists in the MWIR where little or no atmospheric compensation work has been done(More)
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