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Uric acid and the development of hypertension: the normative aging study.

• Todd S. Perlstein, Olga Gumieniak, +5 authors Augusto A Litonjua
• Hypertension
• 2006

Experimental evidence supports a causative role for uric acid in the pathogenesis of hypertension. Prospective studies have variably adjusted for relevant confounders and have been of relatively… (More)

Long-term multivitamin supplementation and cognitive function in men: a randomized trial.

• Francine n Grodstein, Jacqueline O'Brien, +8 authors Howard D Sesso
• Annals of internal medicine
• 2013

BACKGROUND Despite widespread use of multivitamin supplements, their effect on cognitive health-a critical issue with aging-remains inconclusive. To date, no long-term clinical trials have studied… (More)

TABLE 1 . 1 Five Typical Stages of Epidemiologic Transition in CVD Mortality and Types

• Michael Gaziano
• 2018

The overall increase in the global burden of CVD and the distinct regional patterns result in part from the “epidemiologic transition,” which includes four basic stages (Table 1.1): Pestilence and… (More)

Iron status and risk of cardiovascular disease

• Maria Chiara Corti, Michael Gaziano, Charles H. Hennekens
• Annals of epidemiology
• 1997

Free Iron, as well as other transition metals, can catalyze free radical formation. For this reason iron is tightly bound to transport and storage proteins to prevent their involvement in free… (More)

Prolonged clopidogrel use after bare metal and drug-eluting stent placement: the Veterans Administration drug-eluting stent study.

• David P. Faxon, Elizabeth V. Lawler, Melissa Young, Michael Gaziano, Scott Kinlay
• Circulation. Cardiovascular interventions
• 2012

BACKGROUND Current guidelines recommend combining clopidogrel with aspirin for up to 1 year after coronary stenting, but the value of clopidogrel beyond this time is uncertain. METHODS AND RESULTS… (More)

A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

• Sara Lindström, Stephanie J. Loomis, +25 authors Peter Kraft
• PloS one
• 2017

The Nurses' Health Study (NHS), Nurses' Health Study II (NHSII), Health Professionals Follow Up Study (HPFS) and the Physicians Health Study (PHS) have collected detailed longitudinal data on… (More)

Yield and bias in defining a cohort study baseline from electronic health record data

• Jason L Vassy, Yuk-Lam Ho, +4 authors David Gagnon
• Journal of Biomedical Informatics
• 2018

AIMS Despite growing interest in using electronic health records (EHR) to create longitudinal cohort studies, the distribution and missingness of EHR data might introduce selection bias and… (More)

The genetics of functional disability in schizophrenia and bipolar illness: Methods and initial results for VA cooperative study #572.

• Philip D. Harvey, Larry J. Siever, +12 authors John P Concato
• American journal of medical genetics. Part B…
• 2014

Given the prominence of cognitive impairments and disability associated with schizophrenia and bipolar disorder, substantial interest has arisen in identifying determinants of the diseases and their… (More)

The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002-2012.

• Ariela R. Orkaby, Lisa Nussbaum, +13 authors Jane Ann Driver
• The journals of gerontology. Series A, Biological…
• 2018

Background Frailty is a key determinant of clinical outcomes. We sought to describe frailty among U.S. Veterans and its association with mortality. Methods Nationwide retrospective cohort study of… (More)

lcohol Consumption and Prognosis n Patients With Left Ventricular Systolic ysfunction After a Myocardial Infarction

• A. Aguilar, Hicham Skali, +10 authors Scott Solomon
• 2016

avid Aguilar, MD,* Hicham Skali, MD,* Lemuel A. Moyé, MD, PHD,† Eldrin F. Lewis, MD, MPH,* . Michael Gaziano, MD, MPH,*‡ John D. Rutherford, MD, FACC,§ L. Howard Hartley, MD, FACC,* telio S. Randall,… (More)

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