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  • Isabelle Chantret, Alain Barbat, Elisabeth Dussaulx, Michael G. Brattain, Alain Zweibaum
  • Biology, Medicine
  • Cancer research
  • 1988 (First Publication: 1 April 1988)
  • Twenty human colon carcinoma cell lines were studied for their ability to develop some of the characteristics of the normal intestinal epithelium, e.g., epithelial polarity, presence of theExpand
  • Shazli N. Malik, Michael G. Brattain, +4 authors Jeffrey I. Kreisberg
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 2002 (First Publication: 1 April 2002)
  • PURPOSE Whereas the early stage of prostate cancer is marked by excessive proliferation, in advanced stages of the disease, a decreased apoptotic death rate (increased cell survival) also contributesExpand
  • Jing Wang, Luzhe Sun, +8 authors Michael G. Brattain
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 1995 (First Publication: 15 September 1995)
  • Escape from negative growth regulation by transforming growth factor β (TGF-β) as a result of the loss of TGF-β type II receptor (RII) expression has been found to be associated with the replicationExpand
  • Weiqi Huang, Shujie Zhao, Sudhakar Ammanamanchi, Michael G. Brattain, Kolaparthi Venkatasubbarao, J. W. Jr. Freeman
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2005 (First Publication: 18 March 2005)
  • Transforming growth factor β type II receptor (TβRII) is a tumor suppressor gene that can be transcriptionally silenced by histone deacetylases (HDACs) in cancer cells. In this report, weExpand
  • Jiangen Gong, Sudhakar Ammanamanchi, Tien C. Ko, Michael G. Brattain
  • Biology, Medicine
  • Cancer research
  • 2003 (First Publication: 15 June 2003)
  • We examined transforming growth factor-beta 1 (TGF-beta 1) effects on cell cycle progression of human colon carcinoma FET cells. TGF-beta 1 inhibited DNA synthesis and cyclin-dependent kinase (CDK)Expand
  • Yi Peter Hu, Sandip B Patil, +4 authors Michael G. Brattain
  • Biology, Medicine
  • Cancer research
  • 2008 (First Publication: 1 October 2008)
  • This study identifies a novel cross-talk paradigm between the type I insulin-like growth factor receptor (IGF1R) and epidermal growth factor receptor (EGFR) in colon cancer cells. IGF1R activation byExpand