Michael G. Wise

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This paper describes an adaptive control system for delivering heparin to maintain a desired level of anticoagulation during hemodialysis. Adaptive control was based on sparse measurements of the activated clotting time (ACT) measured in blood samples drawn from the extracorporeal circuit. A model-based control law was used in conjunction with Bayesian(More)
Lumbar punctures were done on 114 consecutive active duty patients referred for evaluation of positive tests for antibodies to the human immunodeficiency virus (HIV). Eighty-eight percent of these patients appeared to have early HIV infections, as evidenced by intact delayed hypersensitivity, T helper lymphocyte counts greater than 400/mm3, and lack of(More)
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