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- Henry Markram, Joachim Lübke, Michael Frotscher, Bert J. Sakmann
- Science
- 1997
Activity-driven modifications in synaptic connections between neurons in the neocortex may occur during development and learning. In dual whole-cell voltage recordings from pyramidal neurons, the… (More)
- Henry Markram, Joachim Lübke, Michael Frotscher, Arnd Roth, Bert J. Sakmann
- The Journal of physiology
- 1997
1. Dual voltage recordings were made from pairs of adjacent, synaptically connected thick tufted layer 5 pyramidal neurones in brain slices of young rat (14-16 days) somatosensory cortex to examine… (More)
- D Zamanillo, Rolf Sprengel, +14 authors Bert J. Sakmann
- Science
- 1999
Gene-targeted mice lacking the L-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor subunit GluR-A exhibited normal development, life expectancy, and fine structure of neuronal… (More)
- Marlene Bartos, Imre Vida, Michael Frotscher, Jörg Geiger, Peter Jonas
- The Journal of neuroscience : the official…
- 2001
Mutual synaptic interactions between GABAergic interneurons are thought to be of critical importance for the generation of network oscillations and for temporal encoding of information in the… (More)
- Marlene Bartos, Imre Vida, +4 authors Péter Jónás
- Proceedings of the National Academy of Sciences…
- 2002
Networks of GABAergic interneurons are of critical importance for the generation of gamma frequency oscillations in the brain. To examine the underlying synaptic mechanisms, we made paired recordings… (More)
- Uwe Beffert, Edwin J. Weeber, +8 authors Joachim Herz
- Neuron
- 2005
Apolipoprotein E receptor 2 (Apoer2), a member of the LDL receptor gene family, and its ligand Reelin control neuronal migration during brain development. Apoer2 is also essential for induction of… (More)
- Kurt Sätzler, Leander F Söhl, +4 authors Joachim H. R. Lübke
- The Journal of neuroscience : the official…
- 2002
The three-dimensional morphology of the axosomatic synaptic structures between a calyx of Held and a principal neuron in the medial nucleus of the trapezoid body (MNTB) in the brainstem of young… (More)
- Jörg Geiger, Joachim Lübke, Arnd Roth, Michael Frotscher, Peter Jonas
- Neuron
- 1997
Glutamatergic transmission at a principal neuron-interneuron synapse was investigated by dual whole-cell patch-clamp recording in rat hippocampal slices combined with morphological analysis. Evoked… (More)
- Xuejun Chai, Eckart Förster, Shanting Zhao, Hans H. Bock, Michael Frotscher
- The Journal of neuroscience : the official…
- 2009
The extracellular matrix protein Reelin, secreted by Cajal-Retzius cells in the marginal zone of the cortex, controls the radial migration of cortical neurons. Reelin signaling involves the… (More)
- Christophe Heinrich, Naoki Nitta, +8 authors Carola A Haas
- The Journal of neuroscience : the official…
- 2006
Mesio-temporal lobe epilepsy (MTLE) is often accompanied by granule cell dispersion (GCD), a widening of the granule cell layer. The molecular determinants of GCD are poorly understood. Here, we used… (More)