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The Ehlers-Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. Over the past two decades, the Villefranche Nosology, which delineated six subtypes, has been widely used as the standard for clinical(More)
PURPOSE The aim of this prospective randomized study was to evaluate the clinical outcome of immediately loaded solid plasma sprayed (TPS) BioComp (BioComp Industries BV, Vught, The Netherlands) implants versus immediate provisionalized but non-loaded BioComp implants in the anterior and premolar region of the maxilla. MATERIALS AND METHODS Forty-eight(More)
CONTEXT Apelin and vasopressin levels are regulated in opposite directions to maintain body fluid homeostasis. OBJECTIVE We thus assessed plasma apelin to copeptin ratios, with plasma copeptin concentrations as a reliable index of vasopressin secretion, in pathological states combining high levels of vasopressin secretion with hyponatremia. DESIGN,(More)
This paper describes a computer-assisted non-existence proof of 9-input sorting networks consisting of 24 comparators, hence showing that the 25-comparator sorting network found by Floyd in 1964 is optimal. As a corollary, we obtain that the 29-comparator network found by Waksman in 1969 is optimal when sorting 10 inputs. This closes the two smallest open(More)
OBJECTIVE To compare two drug regimens to treat resistant hypertension. METHODS In a prospective, randomized, open blinded endpoint study, 167 patients with mean baseline daytime ambulatory blood pressure 135 mmHg or more and/or 85 mmHg or more, despite 4 weeks' treatment with irbesartan 300 mg/day, hydrochlorothiazide 12.5 mg/day and amlodipine 5 mg/day,(More)
This review aims to describe the role and the results of catheter-based renal nerve ablation for the treatment of resistant hypertension. Despite the availability of multiple classes of orally active antihypertensive treatments, resistant hypertension remains an important public health issue in 2012 due to its prevalence and association with target-organ(More)