Michael Ferris

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Disseminated candidiasis is the third leading nosocomial blood stream infection in the United States and is often fatal. We previously showed that disseminated candidiasis was preventable in normal mice by immunization with either a glycopeptide or a peptide synthetic vaccine, both of which were Candida albicans cell wall derived. A weakness of these(More)
OBJECTIVE Our prespecified dose-response analyses of A Very Early Rehabilitation Trial (AVERT) aim to provide practical guidance for clinicians on the timing, frequency, and amount of mobilization following acute stroke. METHODS Eligible patients were aged ≥18 years, had confirmed first (or recurrent) stroke, and were admitted to a stroke unit within 24(More)
Designing yacht rigs using empirical rules of thumb and large margins of safety can result in rigs that are substantially heavier than they need to be. We describe a suite of mathematical programming models for optimizing the dimensions and minimum scantlings of carbon-fibre rigs. By using mixed complementarity models the finite-element analysis of the rig(More)
We investigate a new class of congestion games, called Totally Unimodular (TU) Congestion Games, where the players' strategies are binary vectors inside polyhedra defined by totally unimodular constraint matrices. Network congestion games belong to this class. In the symmetric case, when all players have the same strategy set, we design an algorithm that(More)
The STEP Entity Control System for Concurrent Engineering (SECS/CE) is an archive and version control system that facilitates concurrent engineering by allowing engineers to merge concurrent changes, find conflicts between concurrent changes, ask questions about the contents of changes and designs, and resolve conflicts between design versions produced by(More)
Existing second best toll pricing (SBTP) models determine an optimal toll for a given set of links in a transportation network by minimizing certain system objective, while the traffic flow pattern is assumed to follow user equilibrium (UE). In this paper, we show that such a toll design approach is risk-prone, which tries to optimize for the best-case(More)