Michael Daley

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The hemlock woolly adelgid (HW A; Adelges tsugae Annand) is causing widespread decline and mortality of eastern hemlock (Tsuga canadensis (L.) Carr.) throughout most of the range of eastern hemlock. Stem injection of insecticide is widely used as a chemical control measure, but the effectiveness of this method depends on the hydraulic characteristics of(More)
Although the concept of equivalence for drugs (generics) and biologics (biosimilars) has been readily adopted, the concept of equivalence or indistinguishable characteristics for class III medical devices has yet to be specifically addressed regarding a defined regulatory approval process in the US. In September 2015, GenVisc 850® (sodium hyaluronate), a(More)
Cerebral pressure autoregulation (AR) is a process by which blood flow is kept constant over a specific cerebral perfusion pressure (CPP) range. There have been a number of advances in recent years in the monitoring and modelling of this physiological variable; however, there has been very little work done on the comparison or optimisation of some of the(More)
BACKGROUND Cerebral autoregulation is the process by which cerebral blood flow (CBF) is maintained constant over a specific cerebral perfusion pressure (CPP) range. We have reworked a version of the Ursino and Lodi autoregulation model to derive an index of autoregulation (G), and compared it to a number of other autoregulatory models as well as a gold(More)
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