Michael Dacre

Publications9
h-index4
Citations1,563
Highly Influential Citations73
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The Amphimedon queenslandica genome and the evolution of animal complexity
Sponges are an ancient group of animals that diverged from other metazoans over 600 million years ago. Here we present the draft genome sequence of Amphimedon queenslandica, a demosponge from the… Expand
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The Selaginella Genome Identifies Genetic Changes Associated with the Evolution of Vascular Plants
The genome sequence of a lycophyte hints at ancient evolutionary transitions. Vascular plants appeared ~410 million years ago, then diverged into several lineages of which only two survive: the… Expand
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Genomic Survey of Premetazoans Shows Deep Conservation of Cytoplasmic Tyrosine Kinases and Multiple Radiations of Receptor Tyrosine Kinases
A genomic survey suggests that cytoplasmic tyrosine kinases diversified before the establishment of multicellular organisms. Tracing Tyrosine Kinase Evolution Protein tyrosine kinases, which are… Expand
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Fine-mapping cis-regulatory variants in diverse human populations
Genome-wide association studies (GWAS) are a powerful approach for connecting genotype to phenotype. Most GWAS hits are located in cis-regulatory regions, but the underlying causal variants and their… Expand
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Fine-mapping cis-regulatory variants in diverse human populations
Genome-wide association studies (GWAS) are a powerful approach for connecting genotype to phenotype. Most GWAS hits are located in cis-regulatory regions, but the underlying causal variants and their… Expand
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The Selaginella Genome Identifies Changes in Gene Content Associated With the Evolution of Vascular Plants
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Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping
Background To investigate the epigenetic and transcriptional mechanisms of coronary artery disease (CAD) risk, as well as the functional regulation of chromatin structure and function, we create a… Expand
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Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci
Background To investigate the epigenetic and transcriptional mechanisms of coronary artery disease (CAD) risk, as well as the functional regulation of chromatin structure and function, we have… Expand
Author response: Fine-mapping cis-regulatory variants in diverse human populations