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The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human cancers and for which detailed genetic and pharmacological annotation is available. Here we describe the(More)
The systematic translation of cancer genomic data into knowledge of tumor biology and therapeutic avenues remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human cancers and for which detailed genetic and pharmacologic annotation is available 1. Here we describe the Cancer(More)
A rise in neck pain cases has initiated an exponential interest in the assessment and treatment of cervical spine range of motion (CROM). Experimental limitations, however, have been reported as therapists strive to collect continuous, dynamic data to aid prognosis. This technical report seeks to explore the viability of using inertial sensors to reliably(More)
Automated trust negotiation is the process of establishing trust between entities with no prior relationship through the iterative disclosure of digital credentials. One approach to negotiating trust is for the participants to exchange access control policies to inform each other of the requirements for establishing trust. When a policy is received at(More)
We present an incremental proof of the producer/consumer property for the PCI protocol. In the incremental proof, a corrected model of the multi-bus PCI 2.1 protocol is shown to be a refinement of the producer/consumer property. Multi-bus PCI must be corrected because the original PCI specification violates the producer/consumer property. The final model of(More)
We address the problem of directable weathering of exposed concave rock for use in computer-generated animation or games. Previous weathering models that admit concave surfaces are computationally inefficient and difficult to control. In nature, the spheroidal and cavernous weathering rates depend on the surface curvature. Spheroidal weathering is fastest(More)