This paper develops the concepts and methods of a process we will call "alignment of computational models" or "docking" for short. Alignment is needed to determine whether two models can produce the same results, which in turn is the basis for critical experiments and for tests of whether one model can subsume another. We illustrate our concepts and methods… (More)
SFI Working Papers contain accounts of scientific work of the author(s) and do not necessarily represent the views of the Santa Fe Institute. We accept papers intended for publication in peer-reviewed journals or proceedings volumes, but not papers that have already appeared in print. Except for papers by our external faculty, papers must be based on work… (More)
The Information Lens system is a prototype intelligent information-sharing system that is designed to include not only good user interfaces for supporting the problem-solving activity of individuals, but also good organizational interfaces for supporting the problem-solving activities of groups.
Harnessing Complexity will be indispensable to anyone who wants to better comprehend how people and organizations can adapt effectively in the information age. This book is a step-by-step guide to understanding the...
While complex adaptive systems (CAS) theories focus primarily on phenomena such as systemic robustness against perturbation, self-organization, and on the emergence, transformation, and dissolution of organizational entities or action patterns, the metaphorical resonance of CAS work is not easily translated into careful scientic results. It can be very… (More)
We analyze the role of social structure in maintaining cooperation within a population of adaptive agents for whom cooperative behavior may be costly in the short run. We use the example of a collection of agents playing pairwise Prisoner's Dilemma. We call sustained cooperative behavior in such circumstances a 'cooperative regime'. We show that social… (More)
We examined whether interpersonal closeness increases salivary progesterone. One hundred and sixty female college students (80 dyads) were randomly assigned to participate in either a closeness task with a partner versus a neutral task with a partner. Those exposed to the closeness induction had higher levels of progesterone relative to those exposed to the… (More)
Transfer of a normal Chinese hamster X chromosome (carried in a mouse A9 donor cell line) to a nickel-transformed Chinese hamster cell line with an Xq chromosome deletion resulted in senescense of these previously immortal cells. At early passages of the A9/CX donor cells, the hamster X chromosome was highly active, inducing senescence in 100% of the… (More)
Hospital handoffs are believed to be a key locus of communication breakdown that can endanger patient safety and undermine quality of care. Substantial new efforts to better understand handoffs and to improve handoff practices are under way. Many such efforts appear to be seriously hampered, however, by an underlying presumption that the essential function… (More)