Michael-Christian Lang

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In ten adult patients various clinical signs and symptoms led to the diagnosis of an arachnoid cyst in the anterior and middle cranial fossa. In this study a functional relationship between these cysts and disturbances of higher cognitive processes is described. In addition, neuroendocrinological impairment were caused by arachnoid cysts reaching into the(More)
The timing aspects of human frontal lobe function are discussed in the light of the results of three experiments on movement-related cerebral potentials. Experiment I is based on use of a sequential tracking task and experiment II a motor learning task; experiment III deals with frontal hemispheric specialisation by comparing self-initiated writing and(More)
Twenty right-handed subjects participated in a study investigating the cerebral potentials related to three complex actions: (1) writing one's own signature, (2) drawing a pentagram, and (3) fast meaningless scribbling. The Bereitschaftspotential (BP, readiness potential) started as early as 3 s prior to writing, 2.5 s prior to drawing, but only 1.5 s prior(More)
In the present study, two different physiological parameters were measured to describe brain activity related to visuomotor learning: performance-related DC-potential shifts and regional cerebral blood flow (rCBF) by Tc-99m HMPAO brain SPECT (Single Photon Emission Computerized Tomography). Visuomotor learning was required in a conflicting situation: a(More)
Cortical DC shifts preceding and accompanying the execution of five different bimanual motor tasks were analysed in 20 subjects. All tasks required repetitive flexions and extensions of the two forefingers for a period of at least six seconds. The temporal and spatial structures organization varied in the different tasks: (1) Simultaneous agonistic(More)
OBJECTIVE The aim of the present observational study was to determine the effects of a delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) oromucosal spray (Sativex(®) spray), brand name Sativex(®), indicated for drug-resistant MS spasticity, on the driving ability of treated MS patients. METHODS The study was conducted over a period of 4-6 weeks.(More)
Slow negative potential shifts were recorded together with the error made in motor performance when two different groups of 14 students tracked visual stimuli with their right hand. Various visuomotor tasks were compared. A tracking task (T) in which subjects had to track the stimulus directly, showed no decrease of error in motor performance during the(More)
While there are many behavioural studies available investigating human hand tracking performance, there are none that include recording of cerebral potentials. Sixteen subjects tracked a visual or a tactile target by moving a stylus with their right hand. They voluntarily started the stimulus, which moved for 1 s in a first random direction, then for 1's in(More)