Michael C. Langham

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The effect of hypercapnia on cerebral metabolic rate of oxygen consumption (CMRO(2)) has been a subject of intensive investigation and debate. Most applications of hypercapnia are based on the(More)
We present a technique for quantifying global cerebral metabolic rate of oxygen consumption (CMRO2) in absolute physiologic units at 3-second temporal resolution and apply the technique to quantify(More)
BACKGROUND Endothelial dysfunction present in patients with peripheral artery disease may be better understood by measuring the temporal dynamics of blood flow and oxygen saturation during reactive(More)