Michael C Locher

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OBJECTIVES The aim of this systematic review was to assess the scientific literature in terms of pre-clinical studies evaluating the influence of material, surface and design on the integration of an implant by hard and soft tissues. The included publications were analysed with regard to the frequency of reporting of criteria being derived from the ARRIVE(More)
BACKGROUND At the Clinic for Radiation Oncology at the Zurich University Hospital (UniversitätsSpital Zürich [USZ]), head-and-neck tumor (HNT) patients have been treated with intensity-modulated radiotherapy (IMRT) since 01/2002 (n 〉 800). This method causes less damage to normal tissues adjacent to the tumor, and thus it was possible in the head/neck(More)
A case is reported of a patient suffering from untraceable pain in the palate. The hyperplastic pterygoid hamulus appeared to be the cause of his discomfort. A computed tomography study on 20 adult patients revealed a wide variation in the anatomy of this region, but a fairly consistent pattern in the left-right relationship in the same patient.
Ziel dieser Studie war es, anhand einer Serie von 24 Stereolithographiemodellen die Wertigkeit dieser Methode für die kraniofaziale Chirurgie zu evaluieren und Indikationen zur Modellherstellung herauszuarbeiten. Es wurden Stereolithographiemodelle von 21 Patienten angefertigt, in 3 Fällen wurden 2 Modelle hergestellt. Das Durchschnittsalter der 7(More)
The presence of frontal sinuses following bilateral fronto-orbital advancement is discussed controversially in the literature. In a retrospective study, 33 patients (18 male and 15 female) were operated on between 1982 and 1993, with at least one year postoperative follow-up and with a minimum age of 6 years at the end of the follow-up period following(More)
Between 1988 and 1992, 14,765 impacted third molars were removed in the Department for Maxillofacial Surgery of the University Hospital and Dental Clinic in Zurich. A report on significant complications is given and compared to previous studies. Special attention is given to major complications which needed hospitalisation and/or surgical intervention, like(More)
The alpha(2)-plasmin inhibitor (A2PI) is a main physiological regulator of the trypsin-like serine proteinase plasmin. It is composed of an N-terminal 15 amino acid fibrin cross-linking polypeptide, a 382-residue serpin domain, and a flexible C-terminal segment. The latter, peptide Asn(398)-Lys(452), and its Lys452Ala mutant were expressed as recombinant(More)
451 arthroscopies of the temporomandibular joint (TMJ) have been performed on 373 patients during 10 years of clinical experience. The complication rate was low (1.77%). Most complications were transient, consisting mainly of temporary deficits of the 5th and 7th cranial nerves. No patient required arthrotomy because of complications, but one patient had to(More)
This 10-year retrospective study analyzed the incidence of malignant transformation of oral lichen planus (OLP). The study also included dysplasia and oral lichenoid lesion (OLL) in the initial biopsy as a potential differential diagnosis. A total of 692 scalpel biopsies were taken from 542 patients (207 [38.2 %] men and 335 [61.8 %] women). Clinical and(More)