Learn More
OBJECTIVE The most common finding on magnetic resonance imaging (MRI) of the brain in preterm infants at term-equivalent age is diffuse excessive high signal intensity (DEHSI) in the white matter. It is unclear whether DEHSI represents a biological abnormality. This study used diffusion-weighted imaging (DWI) to compare apparent diffusion coefficient (ADC)(More)
BACKGROUND AND PURPOSE MR imaging is increasingly used to assess maturation and disease in the preterm brain. Knowledge of the changes in T2 values with increasing postmenstrual age (PMA) will aid image interpretation and help in the objective assessment of maturation and disease of the brain in infants. The aim of this study was to obtain T2 values in the(More)
BACKGROUND An early clinical score predicting an abnormal amplitude-integrated electroencephalogram (aEEG) or moderate-severe hypoxic ischemic encephalopathy (HIE) may allow rapid triage of infants for therapeutic hypothermia. We aimed to determine if early clinical examination could predict either an abnormal aEEG at age 6 hours or moderate-severe HIE(More)
This study describes and evaluates a simple method of neuroprotective hypothermia for infants with hypoxic-ischaemic encephalopathy (HIE). Five term infants with HIE were cooled by applying soft, cold gel bags to the head. A radiant warmer, set to 34 degrees C, servo-controlled the temperature measured at a probe between the infant's back and the mattress.(More)
Fifty-five individuals were tested to determine the pneumococcidal promoting activity of their serum against Types I and II pneumococci. By repeated tests an attempt was made to study the constancy of the degree of their immunity over intervals of 2 to 6 months. In this group were included nine persons with common colds and twelve cases of a severe(More)
BACKGROUND Despite limited evidence, fresh frozen plasma (FFP) transfusions are a relatively common neonatal procedure. OBJECTIVES Quantify FFP usage in our unit; determine indications for transfusions and compliance with published guidelines. METHODS Data were retrospectively collected on infants who received FFP from January 2009 to December 2013. (More)
BACKGROUND Intubation is a common neonatal procedure. Premedication is accepted as a standard of care, but its use is not universal and wide variations exist in practice. OBJECTIVE To evaluate current practices for premedication use prior to elective neonatal intubation in South Africa (SA). METHOD We invited 481 clinicians to participate in a(More)
OBJECTIVES To determine the need for resuscitation at the birth of babies delivered by elective caesarean section (CS) and to record the time spent by doctors attending such deliveries. METHODS Data were collected prospectively on all elective CSs performed at Groote Schuur Hospital over a 3-month period. Data collected included: total time involved for(More)
  • 1