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- Michael Bulger, Mark Groudine
- Cell
- 2011
Biological differences among metazoans and between cell types in a given organism arise in large part due to differences in gene expression patterns. Gene-distal enhancers are key contributors to… (More)
- Kathleen E McGrath, Jenna M. Frame, +5 authors James Palis
- Blood
- 2011
A transient erythromyeloid wave of definitive hematopoietic progenitors (erythroid/myeloid progenitors [EMPs]) emerges in the yolk sac beginning at embryonic day 8.25 (E8.25) and colonizes the liver… (More)
- Mustafa Nuri Yenerel, Inger Birgitta Sundell, Joleen Weese, Michael Bulger, Diana M Gilligan
- Experimental hematology
- 2005
OBJECTIVE
The first objective of this study was to examine the differences in levels of adducin (ADD1, ADD2, ADD3) mRNA expression during human erythropoiesis. The second objective was to determine… (More)
- George Fromm, Michael Bulger
- Biochemistry and cell biology = Biochimie et…
- 2009
The beta-globin gene cluster in mammals, consisting of a set of erythroid-specific, developmentally activated, and (or) silenced genes, has long presented a model system for the investigation of gene… (More)
The β-globin locus control region (LCR) is a large DNA element that is required for high-level expression of β-like globin genes from the endogenous mouse locus or in transgenic mice carrying the… (More)
- Xiao Hu, Michael Bulger, +5 authors Steven Fiering
- 2003
Mammalian β-globin loci contain multiple β-like genes that are expressed at different times during development. The murine β-globin locus contains two genes expressed during the embryo stage, Ey and… (More)
- Christopher James Tucker, Soumyaroop Bhattacharya, +7 authors Elena Rustchenko
- Scientific Reports
- 2018
Candida albicans is a diploid fungus and a predominant opportunistic human pathogen. Notably, C. albicans employs reversible chromosomal aneuploidies as a means of survival in adverse environments.… (More)
- Michael Bulger
- Cell stem cell
- 2012
Enormous progress has been made in identifying chromatin "signatures" that define tissue-specific transcriptional networks. Three recent studies by Rada-Iglesias et al. (2012), Wamstad et al. (2012),… (More)
The locus control region (LCR) was thought to be necessary and sufficient for establishing and maintaining an open beta-globin locus chromatin domain in the repressive environment of the developing… (More)
- George Fromm, Christiaan de Vries, +6 authors Michael Bulger
- Blood
- 2009
Active gene promoters are associated with covalent histone modifications, such as hyperacetylation, which can modulate chromatin structure and stabilize binding of transcription factors that… (More)