Michael Buchholz

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The Zscan4 family of genes, encoding SCAN-domain and zinc finger-containing proteins, has been implicated in the control of early mammalian embryogenesis as well as the regulation of pluripotency and maintenance of genome integrity in mouse embryonic stem cells. However, many features of this enigmatic family of genes are poorly understood. Here we show(More)
StarD10 is a dual specificity lipid transfer protein capable of shuttling phosphatidylcholine and phosphatidylethanolamine between membranes in vitro. We now provide evidence that, in vivo, StarD10 is phosphorylated on serine 284. This novel phosphorylation site was identified by tandem mass spectrometry of immunoaffinity-purified StarD10 from lysates of(More)
In this paper a nonlinear model for a heavy dry clutch system with concentric pneumatic actuation is proposed and validated with measurement data. On/off solenoid valves are used for controlling the air stream in and out of the actuator. The different challenges in modeling this system are addressed and discussed to succeed in deriving an appropriate(More)
In this paper we propose a new approach for the control of discrete-time piecewise affine hybrid systems on full-dimensional polytopes. The new strategy is divided into a local and a supervisory control problem. The local problem is to reach and cross one facet of a polytope ensuring that the next sample of the time-discrete trajectory is picked up in the(More)
In this paper we propose an enhanced local control strategy for the control of discrete-time piecewise affine systems on full-dimensional polytopes. The control strategy is divided into a local control and a supervisory control problem. The local control problem is to reach and cross one selected facet of a polytope ensuring that the next sample of the(More)
A long life time and safe operation are important issues when polymer electrolyte membrane fuel cell (PEMFC) stacks are used as power supply in technical systems. Therefore, methods are needed to detect deviations from the chosen operating point before any damage to the stack or the environment occurs. In applications like vehicles, the fuel cell operation(More)
This paper presents a novel approach to online velocity trajectory planning for manual energy efficient driving which involves Model Predictive Control (MPC) for map-based anticipatory driving of heavy duty vehicles. The proposed model leads to a Quadratic Programming (QP) optimization problem with sparse matrix structure, allowing to be solved robustly and(More)