Michael Best

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Neurocognitive impairments are observed in depression and associated with poor functioning. This study examined the efficacy and the effectiveness of cognitive remediation with supplemental Internet-based homework in treatment-resistant depression. Participants were randomized to treatment or wait list control conditions. Treatment consisted of 10 weeks of(More)
This position paper presents an approach to computational narrative based in cognitive linguistics and sociolinguistics accounts of conceptual blending, metaphor, and narrative, multimedia semantics, human-centered interface design, and digital media art practice. In particular, as a case study, we describe the Living Liberia Fabric, an AI-based interactive(More)
We use structural estimates of time preferences to customize incentives for a sample of polio vaccinators during a series of door-to-door immunization drives in Pakistan. Our investigation proceeds in three stages. First, we measure time preferences using intertem-poral allocations of vaccinations. Second, we derive the mapping between these structural(More)
Treatment-resistant depression (TRD) refers to a condition where individuals with major depressive disorder have inadequate or no response to treatment. Although functional disability is a prominent and costly feature of treatment resistance, very little is known about the factors that contribute to and maintain functional impairment in TRD. This is the(More)
AIM We examined the factor structure of the Positive and Negative Syndrome Scale (PANSS) in early-episode psychosis and its relationships with functioning at baseline and follow-up. METHODS A total of 240 consecutive admissions to an early intervention in psychosis clinic were assessed at intake to the program with the PANSS, Global Assessment of(More)
BACKGROUND The current study aimed to examine the effects of diagnostic and symptomatic information on auditory linguistic event-related potentials (ERPs) in the listener, in response to speech containing schizophrenia-associated communication abnormalities. METHODS 73 participants listened to conversation segments while continuous EEG was recorded.(More)
INTRODUCTION Schizotypy is phenologically and genetically related to schizophrenia-spectrum illness. Previous studies find cognitive function to be mildly impaired, but specific impairments and their relationship to functioning are not well understood. In this study, we sought to examine how cognitive load affects performance in schizotypy and to examine(More)
Stigma towards individuals diagnosed with schizophrenia continues despite increasing public knowledge about the disorder. Questionnaires are used almost exclusively to assess stigma despite self-report biases affecting their validity. The purpose of this experiment was to implicitly assess stigma towards individuals with schizophrenia by measuring visual(More)