Michael B. Merickel

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We have investigated developmental alterations in the tonotopic projection of the gerbil lateral superior olive. Single neurons were characterized in the frequency domain and the recording site marked with fast green. Transverse tissue sections from the auditory brainstem of each animal were visualized with a video-equipped microscope, and the image was(More)
(1) The oscillatory network underlying centrally programmed feeding in the fresh water pulmonate, Helisoma trivolvis, was studied using intracellular recording and staining techniques. These premotor neurons have been termed cyberchron neurons. (2) Intracellular staining with Procoin yellow has allowed the construction of a soma map and tentative(More)
The detailed schematic diagrams and construction techniques are presented for a single microelectrode voltage clamp. The devices is used to study the membrane processes of small cells not able to be penetrated with the traditional two microelectrode system. The technique utilizes the same microelectrode alternately for current injection and membrane(More)
The accurate segmentation of the brain from three-dimensional medical imagery is important as the basis for visualization, morphometry, surgical planning and intraoperative navigation. The complex and variable nature of brain anatomy makes recognition of the brain boundaries a difficult problem and frustrates segmentation schemes based solely on local image(More)
Magnetic resonance images of intact human breast tissue are evaluated using statistical measures and shape analysis. In this paper, the Mahalanobis distance measurement and a related F-statistical value demonstrate that breast lesions are statistically separable from normal breast tissue. The minimum set of parameters to provide first order statistical(More)
This paper deals with a quantitative analysis of a network of electrically coupled neurons (cyberchrons) in the snail Helisoma trivolvis. This network produces regular bursts of activity which drive the motoneurons controlling the feeding musculature. Analysis of the time constants and Bode plots obtained from current injection leads to the development of(More)
1. The resting potential of the lateral giant neuron in the buccal ganglia of the fresh water snailHelisoma trivolvis becomes more negative with an increase in temperature (Fig. 1). 2. The degree to which the resting potential varies over 3 to 30° C is dependent upon the previous acclimation temperature of the experimental subject (Fig. 6A). 3. Temperature(More)
Automated identification and boundary extraction of blobs in "real world" imagery is a difficult task because the boundaries are so irregular that there is often insufficient a priori information describing these boundaries and traditional methods fail. This paper has proposed a progressive segmentation approach and a boundary estimation method to identify(More)