Michael August

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Angiotensin II infusion causes endothelial dysfunction by increasing NAD(P)H oxidase-mediated vascular superoxide production. However, it remains to be elucidated how in vivo angiotensin II treatment may alter the expression of the gp91(phox) isoforms and the endothelial nitric oxide synthase (NOS III) and subsequent signaling events and whether, in(More)
OBJECTIVE Nebivolol, in contrast to other selective beta1-adrenergic receptor antagonists like atenolol, improves endothelial function in patients with oxidative stress within vascular tissue. With the present studies we sought to determine whether beta receptor blockade with nebivolol may improve endothelial function in hyperlipidemia and whether this is(More)
OBJECTIVE In the present study, we sought to identify mechanisms underlying increased oxidative stress in vascular tissue in an experimental animal model of chronic congestive heart failure (CHF). METHODS AND RESULTS Superoxide and nitric oxide (NO) was measured in vessels from cardiomyopathic hamsters (CHF hamsters) and golden Syrian hamsters. We also(More)
The practicality of existing techniques for processing encrypted data stored in untrusted cloud environments is a limiting factor in the adoption of cloud-based applications. Both public and private sector organizations are reluctant to push their data to the cloud due to strong requirements for security and privacy of their data. In particular,(More)
Cloud services are on-demand services provided to end-users over the Internet and hosted by cloud service providers. A cloud service consists of a set of interacting applications/processes running on one or more interconnected VMs. Organizations are increasingly embracing cloud services as a means of outsourcing their IT departments. However, cloud service(More)
Enabling warfighters to efficiently and safely execute dangerous missions, unmanned systems have been an increasingly valuable component in modern warfare. The evolving use of unmanned systems leads to vast amounts of data collected from sensors placed on the remote vehicles. As a result, many command and control (C2) systems have been developed to provide(More)
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