• Publications
  • Influence
Giant magnetoresistive biochip for DNA detection and HPV genotyping.
  • L. Xu, Heng Yu, +5 authors S. Wang
  • Materials Science, Medicine
  • Biosensors & bioelectronics
  • 15 September 2008
A giant magnetoresistive (GMR) biochip based on spin valve sensor array and magnetic nanoparticle labels was developed for inexpensive, sensitive and reliable DNA detection. The DNA targets detectedExpand
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Molecular characterization of Neisseria gonorrhoeae identifies transmission and resistance of one ciprofloxacin‐resistant strain
A highly discriminative and objective genetic characterization of N. gonorrhoeae, which increases our knowledge of strain populations in different geographic areas, is crucial for the development ofExpand
  • 44
  • 1
Methodological improvements of pyrosequencing technology.
Pyrosequencing technology is a rather novel DNA sequencing method based on the sequencing-by-synthesis principle. This bioluminometric, real-time DNA sequencing technique employs a cascade of fourExpand
  • 36
PathogenMip Assay: A Multiplex Pathogen Detection Assay
The Molecular Inversion Probe (MIP) assay has been previously applied to a large-scale human SNP detection. Here we describe the PathogenMip Assay, a complete protocol for probe production andExpand
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Connector Inversion Probe Technology: A Powerful One-Primer Multiplex DNA Amplification System for Numerous Scientific Applications
We combined components of a previous assay referred to as Molecular Inversion Probe (MIP) with a complete gap filling strategy, creating a versatile powerful one-primer multiplex amplificationExpand
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Detection of gyrA mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by rapid and reliable pre-programmed short DNA sequencing.
Quinolone resistance is rapidly increasing in Neisseria gonorrhoeae and is posing a significant public health threat that requires constant surveillance. A rapid and reliable mutation detection assayExpand
  • 21
Sentinel-base DNA genotyping using multiple sequencing primers for high-risk human papillomaviruses.
Despite the various technologies in place for genotyping human papillomaviruses (HPV), clinical use and clinical research demand a method that is fast, more reliable and cost-effective. TheExpand
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Pyrosequencing of the DNA gyrase gene in Neisseria species: effective indicator of ciprofloxacin resistance in Neisseria gonorrhoeae
The quinolone resistance determining region (QRDR) of the gyrA gene in ciprofloxacin‐susceptible strains (n=53) and strains of Neisseria spp. with reduced susceptibility (n=70) was determined by theExpand
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PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens
TLDR
We describe PathogenMIPer, a software program for designing molecular inversion probe (MIP) oligonucleotides for use in pathogen identification and detection. Expand
  • 18
The Sequencing Bead Array (SBA), a Next-Generation Digital Suspension Array
Here we describe the novel Sequencing Bead Array (SBA), a complete assay for molecular diagnostics and typing applications. SBA is a digital suspension array using Next-Generation Sequencing (NGS),Expand
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